Genetic Basis of SMARCB1 Protein Loss in 22 Sinonasal Carcinomas

SMARCB1-deficient sinonasal carcinoma (SNC) is an aggressive malignancy characterized by INI1 loss mostly due to homozygous SMARCB1 deletion. With the exception of a few reported cases, these tumors have not been thoroughly studied by massive parallel sequencing (MPS). A retrospective cohort of 22 S...

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Vydáno v:Hum Pathol
Hlavní autoři: Dogan, Snjezana, Cotzia, Paolo, Ptashkin, Ryan N., Nanjangud, Gouri J., Xu, Bin, Boroujeni, Amir Momeni, Cohen, Marc A., Pfister, David G., Prasad, Manju L., Antonescu, Cristina R., Chen, Yingbei, Gounder, Mrinal M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669579/
https://ncbi.nlm.nih.gov/pubmed/32818509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2020.08.004
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