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Current Challenges and Opportunities in Designing Protein–Protein Interaction Targeted Drugs

It has been noticed that the efficiency of drug development has been decreasing in the past few decades. To overcome the situation, protein–protein interactions (PPIs) have been identified as new drug targets as early as 2000. PPIs are more abundant in human cells than single proteins and play numer...

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Detalhes bibliográficos
Publicado no:Adv Appl Bioinform Chem
Main Authors: Shin, Woong-Hee, Kumazawa, Keiko, Imai, Kenichiro, Hirokawa, Takatsugu, Kihara, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669531/
https://ncbi.nlm.nih.gov/pubmed/33209039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S235542
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