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Rapid generation of potent antibodies by autonomous hypermutation in yeast
The predominant approach for antibody generation remains animal immunization, which can yield exceptionally selective and potent antibody clones owing to the powerful evolutionary process of somatic hypermutation. However, animal immunization is inherently slow, has poor compatibility with certain a...
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| 出版年: | bioRxiv |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7668743/ https://ncbi.nlm.nih.gov/pubmed/33200136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.11.378778 |
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