Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells

BACKGROUND: Combining radiotherapy (RT) with immuno-oncology (IO) therapy (IORT) may enhance IO-induced antitumor response. Quantitative imaging biomarkers can be used to provide prognosis, predict tumor response in a non-invasive fashion and improve patient selection for IORT. A biologically inspir...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Sun, Roger, Sundahl, Nora, Hecht, Markus, Putz, Florian, Lancia, Andrea, Rouyar, Angela, Milic, Marina, Carré, Alexandre, Battistella, Enzo, Alvarez Andres, Emilie, Niyoteka, Stéphane, Romano, Edouard, Louvel, Guillaume, Durand-Labrunie, Jérôme, Bockel, Sophie, Bahleda, Rastilav, Robert, Charlotte, Boutros, Celine, Vakalopoulou, Maria, Paragios, Nikos, Frey, Benjamin, Soria, Jean-Charles, Massard, Christophe, Ferté, Charles, Fietkau, Rainer, Ost, Piet, Gaipl, Udo, Deutsch, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Immunotherapy Biomarkers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668366/
https://ncbi.nlm.nih.gov/pubmed/33188037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001429
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