Combinations of Radiotherapy with Vaccination and Immune Checkpoint Inhibition Differently Affect Primary and Abscopal Tumor Growth and the Tumor Microenvironment

SIMPLE SUMMARY: Radiotherapy (RT) with higher single doses is capable of creating a beneficial immunological tumor microenvironment for additional immune therapies to trigger systemic anti-tumor immune responses. Here, we aimed to boost RT-induced immune responses with inactivated whole tumor cell v...

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Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Rückert, Michael, Deloch, Lisa, Frey, Benjamin, Schlücker, Eberhard, Fietkau, Rainer, Gaipl, Udo S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916259/
https://ncbi.nlm.nih.gov/pubmed/33572437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040714
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