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Small molecule CDS-3078 induces G(2)/M phase arrest and mitochondria-mediated apoptosis in HeLa cells

The tumor suppressor p53 serves important roles in cell cycle arrest and apoptosis, and its activation increases the sensitivity of cancer cells to radiotherapy or chemotherapy. In the present study, the small molecule 2-[1-(4-(benzyloxy)phenyl)-3-oxoisoindolin-2-yl)-2-(4-methoxyphenyl)] acetic acid...

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Bibliografische gegevens
Gepubliceerd in:Exp Ther Med
Hoofdauteurs: Zhang, Yuanxin, Li, Pengcheng, Rong, Jiamin, Ge, Yakun, Hu, Chenming, Bai, Xu, Shi, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668142/
https://ncbi.nlm.nih.gov/pubmed/33209128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9414
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