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Small molecule CDS-3078 induces G(2)/M phase arrest and mitochondria-mediated apoptosis in HeLa cells

The tumor suppressor p53 serves important roles in cell cycle arrest and apoptosis, and its activation increases the sensitivity of cancer cells to radiotherapy or chemotherapy. In the present study, the small molecule 2-[1-(4-(benzyloxy)phenyl)-3-oxoisoindolin-2-yl)-2-(4-methoxyphenyl)] acetic acid...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Zhang, Yuanxin, Li, Pengcheng, Rong, Jiamin, Ge, Yakun, Hu, Chenming, Bai, Xu, Shi, Wei
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668142/
https://ncbi.nlm.nih.gov/pubmed/33209128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9414
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