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Small molecule CDS-3078 induces G(2)/M phase arrest and mitochondria-mediated apoptosis in HeLa cells
The tumor suppressor p53 serves important roles in cell cycle arrest and apoptosis, and its activation increases the sensitivity of cancer cells to radiotherapy or chemotherapy. In the present study, the small molecule 2-[1-(4-(benzyloxy)phenyl)-3-oxoisoindolin-2-yl)-2-(4-methoxyphenyl)] acetic acid...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7668142/ https://ncbi.nlm.nih.gov/pubmed/33209128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9414 |
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