טוען...
USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L–SMAD pathway
An imbalance in cellular homeostasis occurring as a result of protein misfolding and aggregation contributes to the pathogeneses of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Here, we report the identification of a ubiquitin-specific protease, USP7, as a regulatory sw...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7668097/ https://ncbi.nlm.nih.gov/pubmed/33106424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014349117 |
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