SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health problem. Evasion of IFN-mediated antiviral signaling is a common defense strategy that pathogenic viruses use to replicate a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Miorin, Lisa, Kehrer, Thomas, Sanchez-Aparicio, Maria Teresa, Zhang, Ke, Cohen, Phillip, Patel, Roosheel S., Cupic, Anastasija, Makio, Tadashi, Mei, Menghan, Moreno, Elena, Danziger, Oded, White, Kris M., Rathnasinghe, Raveen, Uccellini, Melissa, Gao, Shengyan, Aydillo, Teresa, Mena, Ignacio, Yin, Xin, Martin-Sancho, Laura, Krogan, Nevan J., Chanda, Sumit K., Schotsaert, Michael, Wozniak, Richard W., Ren, Yi, Rosenberg, Brad R., Fontoura, Beatriz M. A., García-Sastre, Adolfo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668094/
https://ncbi.nlm.nih.gov/pubmed/33097660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016650117
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