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Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution

Toxicity from the external presence or internal production of compounds can reduce the growth and viability of microbial cell factories and compromise productivity. Aromatic compounds are generally toxic for microorganisms, which makes their production in microbial hosts challenging. Here we use ada...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Pereira, Rui, Mohamed, Elsayed T., Radi, Mohammad S., Herrgård, Markus J., Feist, Adam M., Nielsen, Jens, Chen, Yun
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668050/
https://ncbi.nlm.nih.gov/pubmed/33106428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013044117
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