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Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution

Toxicity from the external presence or internal production of compounds can reduce the growth and viability of microbial cell factories and compromise productivity. Aromatic compounds are generally toxic for microorganisms, which makes their production in microbial hosts challenging. Here we use ada...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pereira, Rui, Mohamed, Elsayed T., Radi, Mohammad S., Herrgård, Markus J., Feist, Adam M., Nielsen, Jens, Chen, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668050/
https://ncbi.nlm.nih.gov/pubmed/33106428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013044117
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