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Structural basis for the interaction of Shiga toxin 2a with a C-terminal peptide of ribosomal P stalk proteins
The principal virulence factor of human pathogenic enterohemorrhagic Escherichia coli is Shiga toxin (Stx). Shiga toxin 2a (Stx2a) is the subtype most commonly associated with severe disease outcomes such as hemorrhagic colitis and hemolytic uremic syndrome. The catalytic A1 subunit (Stx2A1) binds t...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7667979/ https://ncbi.nlm.nih.gov/pubmed/32878986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.015070 |
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