Actin-binding protein profilin1 promotes aggressiveness of clear-cell renal cell carcinoma cells

Clear-cell renal cell carcinoma (ccRCC), the most common subtype of renal cancer, has a poor clinical outcome. A hallmark of ccRCC is genetic loss-of-function of VHL (von Hippel–Lindau) that leads to a highly vascularized tumor microenvironment. Although many ccRCC patients initially respond to anti...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Allen, Abigail, Gau, David, Francoeur, Paul, Sturm, Jordan, Wang, Yue, Martin, Ryan, Maranchie, Jodi, Duensing, Anette, Kaczorowski, Adam, Duensing, Stefan, Wu, Lily, Lotze, Michael T., Koes, David, Storkus, Walter J., Roy, Partha
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2020
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667959/
https://ncbi.nlm.nih.gov/pubmed/32883810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013963
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