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Improved Synthesis of [(11)C]COU and [(11)C]PHXY, Evaluation of Neurotoxicity, and Imaging of MAOs in Rodent Heart

[Image: see text] The radiotracers [(11)C]COU and [(11)C]PHXY are potential PET imaging agents for in vivo studies of monoamine oxidases (MAOs), as previously shown in rodent and primate brain. One-pot, automated methods for the radiosynthesis of [(11)C]PHXY and [(11)C]COU were developed to provide...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Brooks, Allen F., Mufarreh, Anthony J., Shao, Xia, Kaur, Tanpreet, Stauff, Jenelle, Arteaga, Janna, Kilbourn, Michael R., Scott, Peter J. H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667825/
https://ncbi.nlm.nih.gov/pubmed/33214844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00419
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