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Suvorexant, a Dual Orexin Receptor Antagonist, Protected Seizure through Interaction with GABA(A) and Glutamate Receptors
Orexin can increase neuronal excitability and induce epileptic activity. In this study, the effects of suvorexant (orexin receptor antagonist) on pentylenetetrazol (PTZ) and maximal electroshock (MES)-induced seizure were investigated. Mice were divided into 5 groups of six animals each including no...
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| Veröffentlicht in: | Iran J Pharm Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Shaheed Beheshti University of Medical Sciences
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7667563/ https://ncbi.nlm.nih.gov/pubmed/33224245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.14688.12584 |
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