Alterations in Opioid Inhibition Cause Widespread Nociception but Do Not Affect Anxiety-Like Behavior in Oral Cancer Mice

Widespread pain and anxiety are commonly reported in cancer patients. We hypothesize that cancer is accompanied by attenuation of endogenous opioid-mediated inhibition, which subsequently causes widespread pain and anxiety. To test this hypothesis we used a mouse model of oral squamous cell carcinom...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Ye, Yi, Bernabé, Daniel G., Salvo, Elizabeth, Viet, Chi T., Ono, Kentaro, Dolan, John C., Janal, Malvin, Aouizerat, Brad E., Miaskowski, Christine, Schmidt, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667485/
https://ncbi.nlm.nih.gov/pubmed/28673713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.06.038
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