Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers

INTRODUCTION: Cancer pain creates a poor quality of life and decreases survival. The basic neurobiology of cancer pain is poorly understood. Adenosine triphosphate (ATP) and the ATP ionotropic receptor subunits, P2X2 and P2X3, mediate cancer pain in animal models; however, it is unknown whether this...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Ye, Yi, Ono, Kentaro, Bernabé, Daniel G, Viet, Chi T, Pickering, Victoria, Dolan, John C, Hardt, Markus, Ford, Anthony P, Schmidt, Brian L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229781/
https://ncbi.nlm.nih.gov/pubmed/24903857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-62
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