A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity

Affordable and effective antiviral therapies are needed worldwide, especially against agents such as dengue virus that are endemic in underserved regions. Many antiviral compounds have been studied in cultured cells but are unsuitable for clinical applications due to pharmacokinetic profiles, side e...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Moshiri, Jasmine, Constant, David A., Liu, Bowen, Mateo, Roberto, Kearnes, Steven, Novick, Paul, Prasad, Ritika, Nagamine, Claude, Pande, Vijay, Kirkegaard, Karla
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667029/
https://ncbi.nlm.nih.gov/pubmed/33173007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02839-20
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