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A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity

Affordable and effective antiviral therapies are needed worldwide, especially against agents such as dengue virus that are endemic in underserved regions. Many antiviral compounds have been studied in cultured cells but are unsuitable for clinical applications due to pharmacokinetic profiles, side e...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Moshiri, Jasmine, Constant, David A., Liu, Bowen, Mateo, Roberto, Kearnes, Steven, Novick, Paul, Prasad, Ritika, Nagamine, Claude, Pande, Vijay, Kirkegaard, Karla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667029/
https://ncbi.nlm.nih.gov/pubmed/33173007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02839-20
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