Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability

BACKGROUND: Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell in the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive caspases, including caspases 3 and 7, play c...

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Bibliografiske detaljer
Udgivet i:Biol Res
Main Authors: Safari, Fatemeh, Farajnia, Safar, Behzad Behbahani, Abbas, Zarredar, Habib, Barekati-Mowahed, Mazyar, Dehghani, Hesam
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666471/
https://ncbi.nlm.nih.gov/pubmed/33187557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-020-00319-x
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