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Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
BACKGROUND: Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell in the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive caspases, including caspases 3 and 7, play c...
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| Publicado no: | Biol Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666471/ https://ncbi.nlm.nih.gov/pubmed/33187557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-020-00319-x |
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