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Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease

Therapies targeting late events in Alzheimer’s disease (AD), including aggregation of amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they are given after significant neuronal damage has occurred. Biomarkers suggest that the earliest event in AD is a decrease of...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Korte, Nils, Nortley, Ross, Attwell, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666276/
https://ncbi.nlm.nih.gov/pubmed/32865691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02215-w
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