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Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease

Therapies targeting late events in Alzheimer’s disease (AD), including aggregation of amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they are given after significant neuronal damage has occurred. Biomarkers suggest that the earliest event in AD is a decrease of...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol
Main Authors: Korte, Nils, Nortley, Ross, Attwell, David
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666276/
https://ncbi.nlm.nih.gov/pubmed/32865691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02215-w
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