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Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease

Therapies targeting late events in Alzheimer’s disease (AD), including aggregation of amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they are given after significant neuronal damage has occurred. Biomarkers suggest that the earliest event in AD is a decrease of...

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Bibliografski detalji
Izdano u:Acta Neuropathol
Glavni autori: Korte, Nils, Nortley, Ross, Attwell, David
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666276/
https://ncbi.nlm.nih.gov/pubmed/32865691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02215-w
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