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Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease
Therapies targeting late events in Alzheimer’s disease (AD), including aggregation of amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they are given after significant neuronal damage has occurred. Biomarkers suggest that the earliest event in AD is a decrease of...
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| Опубликовано в: : | Acta Neuropathol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Berlin Heidelberg
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666276/ https://ncbi.nlm.nih.gov/pubmed/32865691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02215-w |
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