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Quantifying the efficacy of checkpoint inhibitors on CD8(+) cytotoxic T cells for immunotherapeutic applications via single-cell interaction
The inhibition of the PD1/PDL1 pathway has led to remarkable clinical success for cancer treatment in some patients. Many, however, exhibit little to no response to this treatment. To increase the efficacy of PD1 inhibition, additional checkpoint inhibitors are being explored as combination therapy...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7666200/ https://ncbi.nlm.nih.gov/pubmed/33188167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03173-7 |
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