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Scutellarin ameliorates pulmonary fibrosis through inhibiting NF-κB/NLRP3-mediated epithelial–mesenchymal transition and inflammation

Idiopathic pulmonary fibrosis (IPF) is featured with inflammation and extensive lung remodeling caused by overloaded deposition of extracellular matrix. Scutellarin is the major effective ingredient of breviscapine and its anti-inflammation efficacy has been reported before. Nevertheless, the impact...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Peng, Ling, Wen, Li, Shi, Qing-Feng, Gao, Feng, Huang, Bin, Meng, Jie, Hu, Cheng-Ping, Wang, Chang-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666141/
https://ncbi.nlm.nih.gov/pubmed/33188176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03178-2
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