Sphingosine kinase 1 inhibition decreases the epithelial-mesenchymal transition and ameliorates renal fibrosis via modulating NF-κB signaling

Renal fibrosis is a critical process underlying the development progression of chronic kidney disease to end-stage renal disease, which has intrigued much attention. This study aimed to investigate the role of Sphingosine kinase 1 (SphK1) on epithelial-mesenchymal transition (EMT) in renal fibrosis...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: He, Fei, Fan, Maoxiao, Jin, Yansheng, Wang, Haiyan, Ding, Lan, Fan, Jianfeng, Gu, Shuaishuai, Xu, Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789211/
https://ncbi.nlm.nih.gov/pubmed/31632556
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