A Systematic Literature Review and Meta-Analysis Describing the Prevalence of KRAS, NRAS, and BRAF Gene Mutations in Metastatic Colorectal Cancer

BACKGROUND: Tumors of the metastatic colorectal cancer (mCRC) patients that are wildtype (WT) for KRAS or NRAS mutations respond more favorably to anti-epidermal growth factor receptor (EGFR) treatments. Treatment guidelines now recommend that all mCRC patients have WT KRAS and NRAS tumor status con...

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發表在:Gastroenterology Res
Main Authors: Levin-Sparenberg, Elizabeth, Bylsma, Lauren C., Lowe, Kimberly, Sangare, Laura, Fryzek, Jon P., Alexander, Dominik D.
格式: Artigo
語言:Inglês
出版: Elmer Press 2020
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665856/
https://ncbi.nlm.nih.gov/pubmed/33224365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/gr1167
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