T-cell redirecting bispecific antibodies targeting BCMA for the treatment of multiple myeloma

B-cell maturation antigen (BCMA)-targeting bispecific antibodies and bispecific T-cell engagers (BiTEs) redirect T-cells to BCMA-expressing multiple myeloma (MM) cells. These MM cells are subsequently eliminated via various mechanisms of action including the release of granzymes and perforins. Sever...

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Vydáno v:Oncotarget
Hlavní autoři: Verkleij, Christie P.M., Frerichs, Kristine A., Broekmans, Marloes, Absalah, Saida, Maas-Bosman, Patricia W.C., Kruyswijk, Sandy, Nijhof, Inger S., Mutis, Tuna, Zweegman, Sonja, van de Donk, Niels W.C.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Perspective
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665238/
https://ncbi.nlm.nih.gov/pubmed/33227097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27792
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