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Analyzing protein dynamics from fluorescence intensity traces using unsupervised deep learning network

We propose an unsupervised deep learning network to analyze the dynamics of membrane proteins from the fluorescence intensity traces. This system was trained in an unsupervised manner with the raw experimental time traces and synthesized ones, so neither predefined state number nor pre-labelling wer...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Yuan, Jinghe, Zhao, Rong, Xu, Jiachao, Cheng, Ming, Qin, Zidi, Kou, Xiaolong, Fang, Xiaohong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665068/
https://ncbi.nlm.nih.gov/pubmed/33184459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01389-z
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