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Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal common malignancy, with little improvement in patient outcomes over the past decades. Recently, subtypes of pancreatic cancer with different prognoses have been elaborated, however the inability to model these subtypes has precluded mechanis...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Miyabayashi, Koji, Baker, Lindsey A., Deschênes, Astrid, Traub, Benno, Caligiuri, Giuseppina, Plenker, Dennis, Alagesan, Brinda, Belleau, Pascal, Li, Siran, Kendall, Jude, Jang, Gun Ho, Kawaguchi, Risa Karakida, Somerville, Tim D.D., Tiriac, Hervé, Hwang, Chang-Il, Burkhart, Richard A., Roberts, Nicholas J., Wood, Laura D., Hruban, Ralph H., Gillis, Jesse, Krasnitz, Alexander, Vakoc, Christopher R., Wigler, Michael, Notta, Faiyaz, Gallinger, Steven, Park, Youngkyu, Tuveson, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664990/
https://ncbi.nlm.nih.gov/pubmed/32703770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0133
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