Intraductal transplantation models of human pancreatic ductal adenocarcinoma reveal progressive transition of molecular subtypes

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal common malignancy, with little improvement in patient outcomes over the past decades. Recently, subtypes of pancreatic cancer with different prognoses have been elaborated, however the inability to model these subtypes has precluded mechanis...

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Библиографические подробности
Опубликовано в: :Cancer Discov
Главные авторы: Miyabayashi, Koji, Baker, Lindsey A., Deschênes, Astrid, Traub, Benno, Caligiuri, Giuseppina, Plenker, Dennis, Alagesan, Brinda, Belleau, Pascal, Li, Siran, Kendall, Jude, Jang, Gun Ho, Kawaguchi, Risa Karakida, Somerville, Tim D.D., Tiriac, Hervé, Hwang, Chang-Il, Burkhart, Richard A., Roberts, Nicholas J., Wood, Laura D., Hruban, Ralph H., Gillis, Jesse, Krasnitz, Alexander, Vakoc, Christopher R., Wigler, Michael, Notta, Faiyaz, Gallinger, Steven, Park, Youngkyu, Tuveson, David A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664990/
https://ncbi.nlm.nih.gov/pubmed/32703770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0133
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