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Letrozole Suppresses the Fusion of Osteoclast Precursors through Inhibition of p38-Mediated DC-STAMP Pathway

Letrozole is a reversible nonsteroidal aromatase inhibitor that is widely used in postmenopausal breast cancer patients. It is well established that letrozole decreases bone density owing to estrogen depletion; however, few studies have reported its direct effect on bone cells in vitro. Therefore, w...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kim, Hyung Joon, Seong, Hwa-Sik, Choi, YunJeong, Heo, Soon Chul, Kim, Yong-Deok
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664929/
https://ncbi.nlm.nih.gov/pubmed/33182361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218396
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