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DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells
Osteoclasts are bone-resorbing cells that play a pivotal role in bone remodeling. Osteoclasts form large multinuclear giant cells by fusion of mononuclear osteoclasts. How cell fusion is mediated, however, is unclear. We identify the dendritic cell–specific transmembrane protein (DC-STAMP), a putati...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213087/ https://ncbi.nlm.nih.gov/pubmed/16061724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050645 |
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