DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

Osteoclasts are bone-resorbing cells that play a pivotal role in bone remodeling. Osteoclasts form large multinuclear giant cells by fusion of mononuclear osteoclasts. How cell fusion is mediated, however, is unclear. We identify the dendritic cell–specific transmembrane protein (DC-STAMP), a putati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yagi, Mitsuru, Miyamoto, Takeshi, Sawatani, Yumi, Iwamoto, Katsuya, Hosogane, Naobumi, Fujita, Nobuyuki, Morita, Kozo, Ninomiya, Ken, Suzuki, Toru, Miyamoto, Kana, Oike, Yuichi, Takeya, Motohiro, Toyama, Yoshiaki, Suda, Toshio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2005
Gaiak:
Brief Definitive Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213087/
https://ncbi.nlm.nih.gov/pubmed/16061724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050645
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