DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

Osteoclasts are bone-resorbing cells that play a pivotal role in bone remodeling. Osteoclasts form large multinuclear giant cells by fusion of mononuclear osteoclasts. How cell fusion is mediated, however, is unclear. We identify the dendritic cell–specific transmembrane protein (DC-STAMP), a putati...

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Bibliografische gegevens
Hoofdauteurs: Yagi, Mitsuru, Miyamoto, Takeshi, Sawatani, Yumi, Iwamoto, Katsuya, Hosogane, Naobumi, Fujita, Nobuyuki, Morita, Kozo, Ninomiya, Ken, Suzuki, Toru, Miyamoto, Kana, Oike, Yuichi, Takeya, Motohiro, Toyama, Yoshiaki, Suda, Toshio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2005
Onderwerpen:
Brief Definitive Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213087/
https://ncbi.nlm.nih.gov/pubmed/16061724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050645
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