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Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs

Phospholipidosis (PLD), the intracellular accumulation of phospholipids, is an adaptive response to toxic stimuli and serves as an important parameter in the biological assessment of compounds. Cationic amphiphilic drugs are the main inducers of PLD and may impair the function of alveolar macrophage...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Öhlinger, Kristin, Absenger-Novak, Markus, Meindl, Claudia, Ober, Jennifer, Fröhlich, Eleonore
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664898/
https://ncbi.nlm.nih.gov/pubmed/33182310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218391
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