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Differential effects of cotreatment of the antibiotic rifampin with host-directed therapeutics in reducing intracellular Staphylococcus aureus infection

BACKGROUND: Chronic infection by Staphylococcus aureus drives pathogenesis in important clinical settings, such as recurrent pulmonary infection in cystic fibrosis and relapsing infection in osteomyelitis. Treatment options for intracellular S. aureus infection are limited. Rifampin, a lipophilic an...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Evans, Melissa D., Sammelson, Robert, McDowell, Susan
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664464/
https://ncbi.nlm.nih.gov/pubmed/33240647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10330
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