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Differential effects of cotreatment of the antibiotic rifampin with host-directed therapeutics in reducing intracellular Staphylococcus aureus infection

BACKGROUND: Chronic infection by Staphylococcus aureus drives pathogenesis in important clinical settings, such as recurrent pulmonary infection in cystic fibrosis and relapsing infection in osteomyelitis. Treatment options for intracellular S. aureus infection are limited. Rifampin, a lipophilic an...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Evans, Melissa D., Sammelson, Robert, McDowell, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664464/
https://ncbi.nlm.nih.gov/pubmed/33240647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10330
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