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The Cytogenomic “Theory of Everything”: Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging

Mechanisms for somatic chromosomal mosaicism (SCM) and chromosomal instability (CIN) are not completely understood. During molecular karyotyping and bioinformatic analyses of children with neurodevelopmental disorders and congenital malformations (n = 612), we observed colocalization of regular chro...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Iourov, Ivan Y., Vorsanova, Svetlana G., Yurov, Yuri B., Zelenova, Maria A., Kurinnaia, Oxana S., Vasin, Kirill S., Kutsev, Sergei I.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664247/
https://ncbi.nlm.nih.gov/pubmed/33171981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218328
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