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The Cytogenomic “Theory of Everything”: Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging

Mechanisms for somatic chromosomal mosaicism (SCM) and chromosomal instability (CIN) are not completely understood. During molecular karyotyping and bioinformatic analyses of children with neurodevelopmental disorders and congenital malformations (n = 612), we observed colocalization of regular chro...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Iourov, Ivan Y., Vorsanova, Svetlana G., Yurov, Yuri B., Zelenova, Maria A., Kurinnaia, Oxana S., Vasin, Kirill S., Kutsev, Sergei I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664247/
https://ncbi.nlm.nih.gov/pubmed/33171981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218328
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