SCELLECTOR: ranking amplification bias in single cells using shallow sequencing

BACKGROUND: The study of mosaic mutation is important since it has been linked to cancer and various disorders. Single cell sequencing has become a powerful tool to study the genome of individual cells for the detection of mosaic mutations. The amount of DNA in a single cell needs to be amplified be...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Sarangi, Vivekananda, Jourdon, Alexandre, Bae, Taejeong, Panda, Arijit, Vaccarino, Flora, Abyzov, Alexej
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663899/
https://ncbi.nlm.nih.gov/pubmed/33183232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03858-y
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