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SCELLECTOR: ranking amplification bias in single cells using shallow sequencing
BACKGROUND: The study of mosaic mutation is important since it has been linked to cancer and various disorders. Single cell sequencing has become a powerful tool to study the genome of individual cells for the detection of mosaic mutations. The amount of DNA in a single cell needs to be amplified be...
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| Published in: | BMC Bioinformatics |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7663899/ https://ncbi.nlm.nih.gov/pubmed/33183232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03858-y |
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