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Chemical Space Exploration of Oxetanes

This paper focuses on new derivatives bearing an oxetane group to extend accessible chemical space for further identification of kinase inhibitors. The ability to modulate kinase activity represents an important therapeutic strategy for the treatment of human illnesses. Known as a nonclassical isost...

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Pubblicato in:Int J Mol Sci
Autori principali: Alves, Fernando Rodrigues de Sá, Couñago, Rafael M., Laufer, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663787/
https://ncbi.nlm.nih.gov/pubmed/33147789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218199
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