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Chemical Space Exploration of Oxetanes

This paper focuses on new derivatives bearing an oxetane group to extend accessible chemical space for further identification of kinase inhibitors. The ability to modulate kinase activity represents an important therapeutic strategy for the treatment of human illnesses. Known as a nonclassical isost...

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Publicat a:Int J Mol Sci
Autors principals: Alves, Fernando Rodrigues de Sá, Couñago, Rafael M., Laufer, Stefan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663787/
https://ncbi.nlm.nih.gov/pubmed/33147789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218199
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