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Novel Pathway of Adenosine Generation in the Lungs from NAD(+): Relevance to Allergic Airway Disease

Adenosine and uric acid (UA) play a pivotal role in lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). In the present experiments, we measured adenosine synthesis from nicotinamide adenine dinucleotide (NAD(+)) in membranes prepared from wild type (WT) and CD38 knockout (...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Graeff, Richard, Guedes, Alonso, Quintana, Ruth, Wendt-Hornickle, Erin, Baldo, Caroline, Walseth, Timothy, O’Grady, Scott, Kannan, Mathur
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663290/
https://ncbi.nlm.nih.gov/pubmed/33120985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25214966
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