Nalaganje...

Discovery of 5-Phenoxy-2-aminopyridine Derivatives as Potent and Selective Irreversible Inhibitors of Bruton’s Tyrosine Kinase

As a member of the tyrosine protein kinase Tec (TEC) family, Bruton’s tyrosine kinase (BTK) is considered a promising therapeutic target due to its crucial roles in the B cell receptor (BCR) signaling pathway. Although many types of BTK inhibitors have been reported, there is an unmet need to achiev...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Lee, Eun, Cho, Hyewon, Lee, Da Kyung, Ha, JuHyun, Choi, Byeong Jo, Jeong, Ji Hye, Ryu, Jae-Ha, Kang, Jong Soon, Jeon, Raok
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663149/
https://ncbi.nlm.nih.gov/pubmed/33126415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218006
Oznake: Označite
Brez oznak, prvi označite!