Caenorhabditis elegans algn-2 Is Critical for Longevity Conferred by Enhanced Nonsense-Mediated mRNA Decay

Nonsense-mediated mRNA decay (NMD) is a biological surveillance mechanism that eliminates mRNA transcripts with premature termination codons. In Caenorhabditis elegans, NMD contributes to longevity by enhancing RNA quality. Here, we aimed at identifying NMD-modulating factors that are crucial for lo...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Kim, Eun Ji E., Son, Heehwa G., Park, Hae-Eun H., Jung, Yoonji, Kwon, Sujeong, Lee, Seung-Jae V.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662852/
https://ncbi.nlm.nih.gov/pubmed/33225240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101713
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