Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K–AKT Pathway

Triple-negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of biological targets and poor sensitivity to conventional therapies. Chemotherapy is the main clinical therapy, but the effective screening strategy for chemotherapy drugs is poorly investigated. Drug repositioni...

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Vydáno v:Front Oncol
Hlavní autoři: Zhang, Daoyu, An, Xinglan, Li, Qi, Man, Xiaxia, Chu, Meiran, Li, Hao, Zhang, Nan, Dai, Xiangpeng, Yu, Hao, Li, Ziyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662440/
https://ncbi.nlm.nih.gov/pubmed/33194583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.524922
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