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Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K–AKT Pathway

Triple-negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of biological targets and poor sensitivity to conventional therapies. Chemotherapy is the main clinical therapy, but the effective screening strategy for chemotherapy drugs is poorly investigated. Drug repositioni...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhang, Daoyu, An, Xinglan, Li, Qi, Man, Xiaxia, Chu, Meiran, Li, Hao, Zhang, Nan, Dai, Xiangpeng, Yu, Hao, Li, Ziyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662440/
https://ncbi.nlm.nih.gov/pubmed/33194583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.524922
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