NTNU intranasal naloxone trial (NINA-1) study protocol for a double-blind, double-dummy, non-inferiority randomised controlled trial comparing intranasal 1.4 mg to intramuscular 0.8 mg naloxone for prehospital use

INTRODUCTION: Intranasal (IN) naloxone is widely used to treat opioid overdoses. The advantage of nasal administration compared with injection lies in its suitability for administration by lay people as it is needless. Approved formulations of nasal naloxone with bioavailability of approximately 50%...

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Vydáno v:BMJ Open
Hlavní autoři: Skulberg, Arne Kristian, Tylleskär, Ida, Braarud, Anne-Cathrine, Dale, Jostein, Heyerdahl, Fridtjof, Mellesmo, Sindre, Valberg, Morten, Dale, Ola
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2020
Témata:
Emergency Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662429/
https://ncbi.nlm.nih.gov/pubmed/33184084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-041556
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