Effect of Intranasal vs Intramuscular Naloxone on Opioid Overdose: A Randomized Clinical Trial

IMPORTANCE: Previous unblinded clinical trials suggested that the intranasal route of naloxone hydrochloride was inferior to the widely used intramuscular route for the reversal of opioid overdose. OBJECTIVE: To test whether a dose of naloxone administered intranasally is as effective as the same do...

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Vydáno v:JAMA Netw Open
Hlavní autoři: Dietze, Paul, Jauncey, Marianne, Salmon, Allison, Mohebbi, Mohammadreza, Latimer, Julie, van Beek, Ingrid, McGrath, Colette, Kerr, Debra
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902775/
https://ncbi.nlm.nih.gov/pubmed/31722024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.14977
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