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Structural Insights into β-arrestin/CB1 Receptor Interaction: NMR and CD Studies on Model Peptides

Activation of the cannabinoid CB1 receptor induces different cellular signaling cascades through coupling to different effector proteins (G-proteins and β-arrestins), triggering numerous therapeutic effects. Conformational changes and rearrangements at the intracellular domain of this GPCR receptor...

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Pubblicato in:Int J Mol Sci
Autori principali: Morales, Paula, Bruix, Marta, Jiménez, M. Angeles
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662265/
https://ncbi.nlm.nih.gov/pubmed/33143110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218111
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