Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells

The role of Ras-Mitogen-activated protein kinase (MAPK) signaling in cellular aging is not precisely understood. Recently, we identified Sprouty1 (SPRY1) as a weight-loss target gene in human adipose stem/progenitor cells (ASCs) and showed that Sprouty1 is important for proper regulation of adipogen...

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Pubblicato in:J Gerontol A Biol Sci Med Sci
Autori principali: Mandl, Markus, Wagner, Sonja A, Hatzmann, Florian M, Ejaz, Asim, Ritthammer, Heike, Baumgarten, Saphira, Viertler, Hans P, Springer, Jochen, Zwierzina, Marit E, Mattesich, Monika, Brucker, Camille, Waldegger, Petra, Pierer, Gerhard, Zwerschke, Werner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7662188/
https://ncbi.nlm.nih.gov/pubmed/32304210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glaa098
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